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danazol will increase the degree or result of modafinil by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Minor/Significance Unknown.Belzutifan is really a CYP2C19 substrate. Coadministration with CYP2C19 inhibitors may perhaps increase incidence or severity of adverse effects. Keep track of for anemia and hypoxia and cut down belzutifan do